Barbiturate Screen and Confirmation

This page explains the barbiturate screen and confirmation, what it measures, and how to arrange it. A barbiturate screen and confirmation checks blood for barbiturate drugs, which are sedatives that slow brain activity. It is ordered when a person has symptoms like confusion or extreme drowsiness, or as part of a drug monitoring program. The screen gives a quick answer, and the confirmation verifies any positive result.

Sample type
blood
Category
Drug & Urine Screening
Turnaround
1-3 business days
Price
$158
Referral
Not required

A barbiturate screen and confirmation checks blood for barbiturate drugs, which are sedatives that slow brain activity. It is ordered when a person has symptoms like confusion or extreme drowsiness, or as part of a drug monitoring program. The screen gives a quick answer, and the confirmation verifies any positive result.

What it measures

  • Barbiturate screen — A rapid test that shows whether any barbiturate may be present.
  • Confirmation test — A more precise method that identifies the specific barbiturate and its amount.
  • Specific barbiturates — Examples include phenobarbital, secobarbital, and pentobarbital.

Who it is for

Doctors order this test for people with unexplained sedation, confusion, or a known or suspected overdose. It may also be used in monitoring during treatment for barbiturate use.

Preparation

No special preparation, such as fasting, is usually needed. Tell the person drawing your blood about any medicines you take, because some can affect the test.

Results and what they mean

Results are reported as positive or negative for the screen, and the confirmation lists which barbiturate was found and its level. A clinician interprets these results along with your symptoms and history. This is general information, not medical advice; talk with a healthcare professional about your results.

How to order this test

  1. Choose the test and place a confidential order online.
  2. Select a certified collection site and pick a time that suits you.
  3. Have your specimen collected — most draws take only a few minutes.
  4. Review results in a secure portal, typically within 1–3 days.

Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.

Frequently asked questions

Is this test done on blood or urine?

This test uses a blood sample. A urine test may also be used, but that is a different sample type.

How long does it take to get results?

Typical turnaround is 1 to 3 business days, though it can vary by lab.

Can foods or other medicines cause a false positive?

Some medicines can interfere with the screen. The confirmation step helps rule out false positives.

Do I need to stop taking my prescribed barbiturate before the test?

Do not stop any prescribed medicine without talking to your doctor first. They will tell you if any changes are needed.

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