Estradiol Blood Test
This page explains the estradiol blood test, what it measures, and how to arrange it. An estradiol blood test measures the level of estradiol, the main form of estrogen, in your blood. It is ordered to evaluate hormone balance, menstrual or fertility concerns, and to monitor certain hormone treatments.
- Sample type
- blood
- Category
- Hormone
- Turnaround
- 1-3 business days
- Price
- $198
- Referral
- Not required
An estradiol blood test measures the level of estradiol, the main form of estrogen, in your blood. It is ordered to evaluate hormone balance, menstrual or fertility concerns, and to monitor certain hormone treatments.
What it measures
- Estradiol (E2) — The primary estrogen made by the ovaries and, in smaller amounts, by other tissues.
- Total estradiol — The overall amount of estradiol circulating in the blood.
- Free estradiol — The small portion not bound to proteins and available to body tissues.
- Related hormones — Sometimes measured alongside FSH, LH, or progesterone to give context.
Who it is for
A clinician such as a primary care provider, gynecologist, or endocrinologist typically orders this test. It may be requested for fertility evaluation, menstrual changes, menopause symptoms, or monitoring hormone therapy.
Preparation
Preparation depends on why the test is ordered; some providers ask for a specific day of your menstrual cycle. Fasting is usually not required unless other tests are done at the same time.
Results and what they mean
Results are reported as a number in picograms per milliliter (pg/mL) or similar units, often with a reference range that varies by age, sex, and cycle timing. A clinician interprets your result alongside your symptoms and history. This is general information, not medical advice; discuss your results with a qualified healthcare professional.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Frequently asked questions
Do I need to fast for an estradiol test?
Usually no. Fasting is generally not required unless your provider orders other tests that need it.
When in my cycle should I take the test?
Your provider may ask you to test on a specific cycle day. Follow their instructions, since timing can affect the result.
How long do results take?
Results are typically available within 1 to 3 business days.
Can I take hormone medication before the test?
Ask your provider. Some medications can affect estradiol levels, and they may adjust timing or instructions.