Isocyanate MDI Allergy Test
Isocyanate MDI Allergy Test is a laboratory test you can order directly. The Isocyanate MDI Allergy Test is a blood test that checks for allergic sensitization to methylene diphenyl diisocyanate (MDI), a chemical used in polyurethane foams, coatings, and adhesives. It is ordered when a person has work-related or home-related symptoms such as wheezing, nasal congestion, or skin reactions after exposure to MDI-containing products.
- Sample type
- blood
- Category
- Allergy
- Turnaround
- 1-3 business days
- Price
- $49
- Referral
- Not required
The Isocyanate MDI Allergy Test is a blood test that checks for allergic sensitization to methylene diphenyl diisocyanate (MDI), a chemical used in polyurethane foams, coatings, and adhesives. It is ordered when a person has work-related or home-related symptoms such as wheezing, nasal congestion, or skin reactions after exposure to MDI-containing products.
What it measures
- MDI-specific IgE — Antibody that may indicate allergic sensitization to MDI.
- Total IgE — Overall allergy antibody level, sometimes used for context.
- Other isocyanate IgEs — Related isocyanates such as TDI or HDI may be checked together.
- Inhalant allergen panel — Common airborne allergens may be tested to rule out other causes.
Who it is for
It is usually ordered by allergists, occupational medicine physicians, or primary care clinicians for people with suspected MDI-related allergy, especially those working with paints, foams, or adhesives.
Preparation
No fasting is required. Tell your clinician about all medicines, especially antihistamines, because some can affect allergy test results.
Results and what they mean
Results are reported as negative or positive, often with a numeric level for MDI-specific IgE. A positive result suggests sensitization but does not by itself mean you have an allergy or predict how severe symptoms will be. A clinician interprets the results alongside your symptoms and exposure history. This is general information, not medical advice.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the isocyanate mdi allergy test is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
Do I need to stop my allergy medicine before this test?
Some antihistamines can affect allergy testing. Ask your clinician whether you should pause them and for how long.
What does a positive result mean?
It means your blood has antibodies that react to MDI. Your clinician will consider your symptoms and exposure to decide what it means for you.
Can this test tell me if my workplace caused my symptoms?
It can show sensitization, but it cannot prove where or when exposure happened. Your work history and symptom pattern help clarify that.
How long until I get results?
Typical turnaround is 1 to 3 business days after the sample reaches the lab.