Sickle Cell Anemia Screening Test
Below is a plain-language overview of the sickle cell anemia screening test. The sickle cell anemia screening test checks whether you carry the gene for sickle cell disease or have the disease itself. It is ordered for newborns, before pregnancy, or when symptoms suggest a blood disorder.
- Sample type
- blood
- Category
- Anemia & Iron
- Turnaround
- 1-3 business days
- Price
- $118
- Referral
- Not required
The sickle cell anemia screening test checks whether you carry the gene for sickle cell disease or have the disease itself. It is ordered for newborns, before pregnancy, or when symptoms suggest a blood disorder.
What it measures
- Hemoglobin S (HbS) — The abnormal hemoglobin that causes red blood cells to become sickle-shaped.
- Hemoglobin A (HbA) — Normal hemoglobin; its presence shows how many normal genes you have.
- Hemoglobin F (HbF) — Fetal hemoglobin, often higher in newborns and some forms of sickle cell disease.
- Hemoglobin C (HbC) — Another abnormal hemoglobin that can combine with HbS.
Who it is for
Doctors order this test for newborns as part of routine screening, for adults before having children, or when a person has symptoms like pain crises or anemia.
Preparation
No fasting or special preparation is needed. A blood sample is taken from a vein or a heel prick in newborns.
Results and what they mean
Results are reported as the types of hemoglobin found and whether the sickle cell gene is present. A clinician interprets these results along with your health history. This is general information, not medical advice.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the sickle cell anemia screening test is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
Does a positive result mean I have sickle cell disease?
Not always. It can mean you carry the gene (trait) or have the disease. Your doctor will explain which one based on the pattern of hemoglobins.
Is this test painful?
It uses a standard blood draw or a heel prick for babies. Most people feel only a brief pinch.
Can I eat before the test?
Yes, eating and drinking normally is fine. No fasting is required.
How long do results take?
Results are usually ready in 1 to 3 business days.