Trans-hormone Wellness Panel

The Trans-hormone Wellness Panel is a blood test that measures key hormone levels to support monitoring of gender-affirming hormone therapy. It helps clinicians assess whether hormone levels are in a target range and check related health markers.

What it measures

Estradiol — Main form of estrogen; used to monitor feminizing therapy.
Testosterone (total) — Primary androgen; used to monitor masculinizing therapy or suppression.
Luteinizing hormone (LH) — Pituitary hormone that can indicate whether testosterone or estrogen production is suppressed.
Follicle-stimulating hormone (FSH) — Another pituitary hormone often checked alongside LH.
Prolactin — Hormone that can rise with some estrogen therapies; monitored for safety.
Liver enzymes (AST/ALT) — Basic liver health markers, since some hormones are processed by the liver.

Who it is for

It is typically ordered by clinicians managing gender-affirming care, such as endocrinologists, primary care providers, or other healthcare professionals experienced in transgender health.

Preparation

Fasting is not usually required. Timing may matter if you use topical or injectable hormones; follow your clinician's instructions about when to draw blood relative to your last dose.

Results and what they mean

Results are reported as numeric values with reference ranges that may differ from standard ranges because target ranges for hormone therapy are individualized. A clinician interprets the results in the context of your treatment plan, symptoms, and other health factors. This is general information, not medical advice; discuss your results with your healthcare provider.

How to order this test

Choose the test and place a confidential order online.
Select a certified collection site and pick a time that suits you.
Have your specimen collected — most draws take only a few minutes.
Review results in a secure portal, typically within 1–3 days.

Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.

Availability by state

Direct-access online ordering for the trans-hormone wellness panel is available in most states. It is currently unavailable in 6 states:

Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →

Frequently asked questions

Do I need to fast for this test?

Fasting is not typically required. Your clinician will tell you if any special preparation is needed.

How often should I get this panel?

Frequency depends on your treatment stage and clinician's recommendations. It is often checked every few months initially, then less often once levels are stable.

Will my results be kept private?

Yes, your results are confidential and protected by privacy laws. Only you and your healthcare team can access them.

Can I adjust my hormone dose based on these results?

No. Only your prescribing clinician should adjust your dose. Do not change your medication without talking to them first.